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Gene silencing dynamics are modulated by transiently active regulatory elements.
Vermunt, Marit W; Luan, Jing; Zhang, Zhe; Thrasher, A Josephine; Huang, Anran; Saari, Megan S; Khandros, Eugene; Beagrie, Robert A; Zhang, Shiping; Vemulamada, Pranay; Brilleman, Matilda; Lee, Kiwon; Yano, Jennifer A; Giardine, Belinda M; Keller, Cheryl A; Hardison, Ross C; Blobel, Gerd A.
Affiliation
  • Vermunt MW; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. Electronic address: vermuntm@chop.edu.
  • Luan J; Medical Scientist Training Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Zhang Z; Department of Biomedical and Health Informatics, The Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.
  • Thrasher AJ; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Huang A; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Saari MS; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Khandros E; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Beagrie RA; Chromatin and Disease Group, Wellcome Centre for Human Genetics, Oxford OX3 7BN, UK.
  • Zhang S; Department of Biomedical and Health Informatics, The Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.
  • Vemulamada P; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Brilleman M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Lee K; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Yano JA; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Giardine BM; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
  • Keller CA; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
  • Hardison RC; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
  • Blobel GA; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. Electronic address: blobel@chop.edu.
Mol Cell ; 83(5): 715-730.e6, 2023 03 02.
Article in En | MEDLINE | ID: mdl-36868189
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regulatory Sequences, Nucleic Acid / Genome-Wide Association Study Limits: Animals Language: En Journal: Mol Cell Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regulatory Sequences, Nucleic Acid / Genome-Wide Association Study Limits: Animals Language: En Journal: Mol Cell Year: 2023 Document type: Article