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PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1.
Poli, Alessandro; Pennacchio, Fabrizio A; Ghisleni, Andrea; di Gennaro, Mariagrazia; Lecacheur, Margaux; Nastaly, Paulina; Crestani, Michele; Pramotton, Francesca M; Iannelli, Fabio; Beznusenko, Galina; Mironov, Alexander A; Panzetta, Valeria; Fusco, Sabato; Sheth, Bhavwanti; Poulikakos, Dimos; Ferrari, Aldo; Gauthier, Nils; Netti, Paolo A; Divecha, Nullin; Maiuri, Paolo.
Affiliation
  • Poli A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. allen2315@gmail.com.
  • Pennacchio FA; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Ghisleni A; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • di Gennaro M; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Lecacheur M; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Nastaly P; Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Crestani M; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Pramotton FM; EMPA-Materials Science and Technology, Dubenforf, Switzerland.
  • Iannelli F; Institute for Mechanical Systems, ETH, Zurich, Switzerland.
  • Beznusenko G; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Mironov AA; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Panzetta V; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
  • Fusco S; Department of Chemical, Materials and Production Engineering, University of Naples Federico II, Naples, Italy.
  • Sheth B; Centro di Ricerca Interdipartimentale sui Biomateriali CRIB, University of Naples Federico II, Naples, Italy.
  • Poulikakos D; Istituto Italiano di Tecnologia, IIT@CRIB, Naples, Italy.
  • Ferrari A; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
  • Gauthier N; Inositide Laboratory, School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, United Kingdom.
  • Netti PA; Institute for Mechanical Systems, ETH, Zurich, Switzerland.
  • Divecha N; Institute for Mechanical Systems, ETH, Zurich, Switzerland.
  • Maiuri P; IFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy.
Nat Commun ; 14(1): 1432, 2023 03 14.
Article in En | MEDLINE | ID: mdl-36918565
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 Database: MEDLINE Main subject: Heterochromatin / Neoplasms Limits: Humans Language: En Journal: Nat Commun Year: 2023 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 / 2_ODS3 Database: MEDLINE Main subject: Heterochromatin / Neoplasms Limits: Humans Language: En Journal: Nat Commun Year: 2023 Document type: Article