Dicentric chromosome breakage in Drosophila melanogaster is influenced by pericentric heterochromatin and occurs in nonconserved hotspots.

Hill, Hunter J; Bonser, Danielle; Golic, Kent G

Hill, Hunter J; Bonser, Danielle; Golic, Kent G.

Affiliation

Hill HJ; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.
Bonser D; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.
Golic KG; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

Genetics ; 224(2)2023 05 26.

Article in En | MEDLINE | ID: mdl-37010100

Subject(s)

Chromosome Breakage; Drosophila melanogaster; Animals; Humans; Drosophila melanogaster/genetics; Heterochromatin/genetics; Centromere; X Chromosome

Key words

DNA damage; FLP; aphidicolin; dicentric chromosome; fragile site; ring chromosome; telomere healing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosome Breakage / Drosophila melanogaster Limits: Animals / Humans Language: En Journal: Genetics Year: 2023 Document type: Article

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