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Nephrolithiasis in two patients on iron chelation therapy: A case report.
Dillon, Hannah; Baker, Zoë; Pena, Adam; Wang, Yuding; Syed, Helal; Sparks, Scott.
Affiliation
  • Dillon H; Division of Urology, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Baker Z; Division of Urology, Children's Hospital Los Angeles, Los Angeles, CA, USA; Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: zobaker@chla.usc.edu.
  • Pena A; Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Wang Y; Division of Urology, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Syed H; Division of Urology, Children's Hospital Los Angeles, Los Angeles, CA, USA.
  • Sparks S; Division of Urology, Children's Hospital Los Angeles, Los Angeles, CA, USA; Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Transfus Apher Sci ; 62(3): 103702, 2023 Jun.
Article in En | MEDLINE | ID: mdl-37055329
ABSTRACT
Drug-induced nephrolithiasis can arise from insoluble components within medications or crystallization of metabolites due to changes in metabolism and urinary pH. The connection between drugs utilized for iron chelation therapy (ICT) and nephrolithiasis is not well understood. In this report, we describe two pediatric patients diagnosed with nephrolithiasis while undergoing treatment with the chelating agents deferasirox, deferiprone, and deferoxamine for iron overload secondary to repeat blood transfusion.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Thalassemia / Iron Overload / Nephrolithiasis Type of study: Etiology_studies Limits: Child / Humans Language: En Journal: Transfus Apher Sci Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Thalassemia / Iron Overload / Nephrolithiasis Type of study: Etiology_studies Limits: Child / Humans Language: En Journal: Transfus Apher Sci Year: 2023 Document type: Article