Advances in Vaccine Adjuvants: Nanomaterials and Small Molecules.
Handb Exp Pharmacol
; 284: 113-132, 2024.
Article
in En
| MEDLINE
| ID: mdl-37059911
ABSTRACT
Adjuvants have been extensively and essentially formulated in subunits and certain inactivated vaccines for enhancing and prolonging protective immunity against infections and diseases. According to the types of infectious diseases and the required immunity, adjuvants with various acting mechanisms have been designed and applied in human vaccines. In this chapter, we introduce the advances in vaccine adjuvants based on nanomaterials and small molecules. By reviewing the immune mechanisms induced by adjuvants with different characteristics, we aim to establish structure-activity relationships between the physicochemical properties of adjuvants and their immunostimulating capability for the development of adjuvants for more effective preventative and therapeutic vaccines.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vaccines
/
Nanostructures
Limits:
Humans
Language:
En
Journal:
Handb Exp Pharmacol
Year:
2024
Document type:
Article