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Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
Blanc, Marine; Lettl, Clara; Guérin, Jérémy; Vieille, Anaïs; Furler, Sven; Briand-Schumacher, Sylvie; Dreier, Birgit; Bergé, Célia; Plückthun, Andreas; Vadon-Le Goff, Sandrine; Fronzes, Rémi; Rousselle, Patricia; Fischer, Wolfgang; Terradot, Laurent.
Affiliation
  • Blanc M; UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France.
  • Lettl C; Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Guérin J; UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France.
  • Vieille A; UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France.
  • Furler S; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Briand-Schumacher S; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Dreier B; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Bergé C; UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France.
  • Plückthun A; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Vadon-Le Goff S; University of Lyon, CNRS UMR5305, Tissue Biology and Therapeutic Engineering Laboratory (LBTI), Lyon, France.
  • Fronzes R; European Institute of Chemistry and Biology, CNRS UMR 5234 Microbiologie Fondamentale et Pathogénicité, Univ. Bordeaux, Pessac, France.
  • Rousselle P; University of Lyon, CNRS UMR5305, Tissue Biology and Therapeutic Engineering Laboratory (LBTI), Lyon, France.
  • Fischer W; Max von Pettenkofer Institute of Hygiene and Medical Microbiology, Faculty of Medicine, LMU Munich, Munich, Germany.
  • Terradot L; UMR 5086 Molecular Microbiology and Structural Biochemistry CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France.
PLoS Pathog ; 19(5): e1011368, 2023 05.
Article in En | MEDLINE | ID: mdl-37155700
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Helicobacter pylori / Helicobacter Infections Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2023 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Helicobacter pylori / Helicobacter Infections Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: PLoS Pathog Year: 2023 Document type: Article