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Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma.
Mendenhall, William M; Beitler, Jonathan J; Saba, Nabil F; Shaha, Ashok R; Nuyts, Sandra; Strojan, Primoz; Bollen, Heleen; Cohen, Oded; Smee, Robert; Ng, Sweet Ping; Eisbruch, Avraham; Ng, Wai Tong; Kirwan, Jessica M; Ferlito, Alfio.
Affiliation
  • Mendenhall WM; Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
  • Beitler JJ; Harold Alfonds Center for Cancer Care, Maine General Hospital, Augusta, ME, USA.
  • Saba NF; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
  • Shaha AR; Department of Head and Neck Surgery and Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Nuyts S; Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
  • Strojan P; Laboratory of Experimental Radiotherapy, Department of Oncology, University of Leuven, Leuven, Belgium.
  • Bollen H; Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.
  • Cohen O; Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven - University of Leuven, Leuven, Belgium.
  • Smee R; Department of Otolaryngology - Head and Neck Surgery and Oncology, Soroka Medical Center, Tel Aviv, Affiliated with Ben Gurion University of the Negev, Beer Sheva, Israel.
  • Ng SP; Department of Radiation Oncology, The Prince of Wales Cancer Centre, Sydney, NSW, Australia.
  • Eisbruch A; Department of Radiation Oncology, Olivia Newton-John Cancer Centre, Austin Health, Melbourne, Australia.
  • Ng WT; Department of Radiation Oncology, University of Michigan Medicine, Ann Arbor, Michigan, USA.
  • Kirwan JM; Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
  • Ferlito A; Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Int J Part Ther ; 9(4): 243-252, 2023.
Article in En | MEDLINE | ID: mdl-37169005
ABSTRACT

Purpose:

To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). Materials and

Methods:

A review of the pertinent literature.

Results:

Proton beam therapy likely results in reduced acute and late toxicity as compared with intensity-modulated radiation therapy (IMRT). The extent of the reduced toxicity, which may be modest, depends on the endpoint and technical factors such as pencil beam versus passive scattered PBT and adaptive replanning. The disease control rates after PBT are likely similar to those after IMRT.

Conclusion:

Proton beam therapy is an attractive option to treat patients with OPSCC. Whether it becomes widely available depends on access.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Int J Part Ther Year: 2023 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Int J Part Ther Year: 2023 Document type: Article