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Gastrointestinal treatment-related adverse events of combined immune checkpoint inhibitors: a meta-analysis.
Karna, Rahul; S Deliwala, Smit; Ramgopal, Balasubramanian; Asawa, Palash; Mishra, Rahul; P Mohan, Babu; Jayakrishnan, Thejus; Grover, Dheera; Kalra, Tanisha; Bhalla, Jaideep; Saraswati, Ushasi; K Gangwani, Manesh; Dhawan, Manish; G Adler, Douglas.
Affiliation
  • Karna R; Internal Medicine, Allegheny Health Network, Pittsburgh, PA, USA.
  • S Deliwala S; Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA, USA.
  • Ramgopal B; Foundation Fellowship Doctor, University Hospital, Southampton NHS Foundation Trust, Southampton, Hampshire, UK.
  • Asawa P; Internal Medicine, Allegheny Health Network, Pittsburgh, PA, USA.
  • Mishra R; Postdoctoral research fellow, Cleveland Clinic, OH, USA.
  • P Mohan B; Gastroenterology & Hepatology, University of Utah Health School of Medicine, Salt Lake City, UT, USA.
  • Jayakrishnan T; Hematology & Oncology, Cleveland Clinic, Cleveland, OH, USA.
  • Grover D; Internal Medicine, University of Connecticut, Hartford, CT, USA.
  • Kalra T; Internal Medicine, SUNY Downstate Health Science University, NY, USA.
  • Bhalla J; Internal Medicine, Cleveland Clinic, Cleveland, OH, USA.
  • Saraswati U; Internal Medicine, Cleveland Clinic, Cleveland, OH, USA.
  • K Gangwani M; Internal Medicine, University of Toledo Medical Center, Toledo, OH, USA.
  • Dhawan M; Gastroenterology & Hepatology, Allegheny Health Network, Pittsburgh, PA, USA.
  • G Adler D; Center for Advanced Therapeutic Endoscopy, Centura Health, Denver, CO, USA.
Immunotherapy ; 15(10): 773-786, 2023 07.
Article in En | MEDLINE | ID: mdl-37190949
The article talks about a type of medicine called immune checkpoint inhibitors that are used to treat cancer. These medicines can sometimes cause problems in the stomach and liver when used in combination with other cancer treatments, which can lead to hospitalization or, rarely, death. We performed a study on 6581 people who took these medicines in combination with another treatment and determined exactly how often these side effects happened. We also looked at which combinations of medicines were safer. This information can help doctors identify the side effects early and treat them. It can also help scientists design more studies to learn more about these side effects and how to prevent them.
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 3_ND / 4_TD Database: MEDLINE Main subject: Immune Checkpoint Inhibitors / Neoplasms Type of study: Systematic_reviews Limits: Humans Language: En Journal: Immunotherapy Year: 2023 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 3_ND / 4_TD Database: MEDLINE Main subject: Immune Checkpoint Inhibitors / Neoplasms Type of study: Systematic_reviews Limits: Humans Language: En Journal: Immunotherapy Year: 2023 Document type: Article