Nickel catalyzed three-component sulfonylation of non-activated alkyl chlorides.
Chem Commun (Camb)
; 59(45): 6889-6892, 2023 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-37198944
ABSTRACT
We describe a nickel-catalyzed three-component sulfonylation of readily available non-activated alkyl chlorides. A wide range of alkyl aryl sulfones can be synthesized from alkyl chlorides, aryl boronic acids, and potassium metabisulfite, a cheap, efficient, and commercially available SO2 source under simple and easy-to-handle reaction conditions. High selectivity can be achieved with a slight excess of phenylboronic acid and a sulfur dioxide source.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chem Commun (Camb)
Year:
2023
Document type:
Article