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Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses.
Westphal, Tim; Mader, Maria; Karsten, Hendrik; Cords, Leon; Knapp, Maximilian; Schulte, Sophia; Hermanussen, Lennart; Peine, Sven; Ditt, Vanessa; Grifoni, Alba; Addo, Marylyn Martina; Huber, Samuel; Sette, Alessandro; Lütgehetmann, Marc; Pischke, Sven; Kwok, William W; Sidney, John; Schulze Zur Wiesch, Julian.
Affiliation
  • Westphal T; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Mader M; German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
  • Karsten H; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Cords L; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Knapp M; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schulte S; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Hermanussen L; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Peine S; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Ditt V; Institute of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Grifoni A; Institute of Transfusion Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Addo MM; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.
  • Huber S; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Sette A; German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
  • Lütgehetmann M; Department for Clinical Immunology of Infectious Diseases, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
  • Pischke S; Institute of Infection Research and Vaccine Development, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kwok WW; Infectious Diseases Unit I, Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Sidney J; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.
  • Schulze Zur Wiesch J; German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Front Immunol ; 14: 1182504, 2023.
Article in En | MEDLINE | ID: mdl-37215095
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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Common Cold / COVID-19 Limits: Humans Language: En Journal: Front Immunol Year: 2023 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Common Cold / COVID-19 Limits: Humans Language: En Journal: Front Immunol Year: 2023 Document type: Article