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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.
Boeynaems, Steven; Dorone, Yanniv; Zhuang, Yanrong; Shabardina, Victoria; Huang, Guozhong; Marian, Anca; Kim, Garam; Sanyal, Anushka; Sen, Nesli-Ece; Griffith, Daniel; Docampo, Roberto; Lasker, Keren; Ruiz-Trillo, Iñaki; Auburger, Georg; Holehouse, Alex S; Kabashi, Edor; Lin, Yi; Gitler, Aaron D.
Affiliation
  • Boeynaems S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, TX 77030, USA; Center for
  • Dorone Y; Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA.
  • Zhuang Y; IDG/McGovern Institute for Brain Research, Tsinghua-Peking Joint Centre for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Shabardina V; Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Passeig Marítim de la Barceloneta 37-49, Barcelona 08003 Catalonia, Spain.
  • Huang G; Department of Cellular Biology and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
  • Marian A; Imagine Institute, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 1163, Paris Descartes Université, 75015 Paris, France.
  • Kim G; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
  • Sanyal A; Department of Genetics, Stanford University, Stanford, CA 94305, USA.
  • Sen NE; Experimental Neurology, Goethe-University Hospital, 60590 Frankfurt, Germany.
  • Griffith D; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA.
  • Docampo R; Department of Cellular Biology and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
  • Lasker K; The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Ruiz-Trillo I; Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Passeig Marítim de la Barceloneta 37-49, Barcelona 08003 Catalonia, Spain; ICREA, Passeig Lluís Companys 23, Barcelona 08010 Catalonia, Spain.
  • Auburger G; Experimental Neurology, Goethe-University Hospital, 60590 Frankfurt, Germany.
  • Holehouse AS; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Biomolecular Condensates, Washington University in St Louis, St. Louis, MO 63130, USA.
  • Kabashi E; Imagine Institute, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 1163, Paris Descartes Université, 75015 Paris, France.
  • Lin Y; IDG/McGovern Institute for Brain Research, Tsinghua-Peking Joint Centre for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Gitler AD; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: agitler@stanford.edu.
Mol Cell ; 83(12): 2020-2034.e6, 2023 Jun 15.
Article in En | MEDLINE | ID: mdl-37295429
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Ataxin-2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Ataxin-2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Year: 2023 Document type: Article