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Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates.
Meng, Qian-Fang; Tai, Wanbo; Tian, Mingyao; Zhuang, Xinyu; Pan, Yuanwei; Lai, Jialin; Xu, Yangtao; Xu, Zhiqiang; Li, Min; Zhao, Guangyu; Yu, Guang-Tao; Yu, Guocan; Chen, Rongchang; Jin, Ningyi; Li, Xiao; Cheng, Gong; Chen, Xiaoyuan; Rao, Lang.
Affiliation
  • Meng QF; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, China.
  • Tai W; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen 518132, China.
  • Tian M; Tsinghua-Peking Center for Life Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.
  • Zhuang X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
  • Pan Y; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
  • Lai J; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, China.
  • Xu Y; Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore 119074, Singapore.
  • Xu Z; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, China.
  • Li M; Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, China.
  • Zhao G; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
  • Yu GT; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
  • Yu G; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
  • Chen R; Stomatological Hospital, Southern Medical University, Guangzhou 510280, China.
  • Jin N; Department of Chemistry, Tsinghua University, Beijing 100084, China.
  • Li X; Institute of Respiratory Disease, Shenzhen People's Hospital, Shenzhen 518020, China.
  • Cheng G; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
  • Chen X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China.
  • Rao L; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen 518132, China.
Sci Adv ; 9(24): eadg3277, 2023 06 16.
Article in En | MEDLINE | ID: mdl-37315135
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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Nanoparticles / COVID-19 Type of study: Etiology_studies Limits: Animals Language: En Journal: Sci Adv Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Nanoparticles / COVID-19 Type of study: Etiology_studies Limits: Animals Language: En Journal: Sci Adv Year: 2023 Document type: Article