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Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults - an AGePOP review.
Demeester, Cleo; Robins, Donnia; Edwina, Angela Elma; Tournoy, Jos; Augustijns, Patrick; Ince, Ibrahim; Lehmann, Andreas; Vertzoni, Maria; Schlender, Jan Frederik.
Affiliation
  • Demeester C; Systems Pharmacology & Medicine, Pharmaceuticals, Bayer AG, Leverkusen 51373, Germany; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Gasthuisberg O&N II, Leuven, Belgium.
  • Robins D; Global CMC Development, Merck KGaA, Frankfurter Straße 250, Darmstadt, Germany; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Zografou, Greece.
  • Edwina AE; Gerontology and Geriatrics Unit, Department of Public Health and Primary care, KU Leuven - University of Leuven, Leuven, Belgium.
  • Tournoy J; Gerontology and Geriatrics Unit, Department of Public Health and Primary care, KU Leuven - University of Leuven, Leuven, Belgium; Department of Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium.
  • Augustijns P; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Gasthuisberg O&N II, Leuven, Belgium.
  • Ince I; Systems Pharmacology & Medicine, Pharmaceuticals, Bayer AG, Leverkusen 51373, Germany.
  • Lehmann A; Global CMC Development, Merck KGaA, Frankfurter Straße 250, Darmstadt, Germany.
  • Vertzoni M; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Zografou, Greece.
  • Schlender JF; Systems Pharmacology & Medicine, Pharmaceuticals, Bayer AG, Leverkusen 51373, Germany. Electronic address: jan-frederik.schlender@novartis.com.
Eur J Pharm Sci ; 188: 106496, 2023 Sep 01.
Article in En | MEDLINE | ID: mdl-37329924
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dietary Supplements / Drug Development Type of study: Prognostic_studies Language: En Journal: Eur J Pharm Sci Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dietary Supplements / Drug Development Type of study: Prognostic_studies Language: En Journal: Eur J Pharm Sci Year: 2023 Document type: Article