ALOX5AP suppresses osteosarcoma progression via Wnt/ß-catenin/EMT pathway and associates with clinical prognosis and immune infiltration.

Han, Guo-Dong; Dai, Jian; Hui, Hong-Xia; Zhu, Jing

Han, Guo-Dong; Dai, Jian; Hui, Hong-Xia; Zhu, Jing.

Affiliation

Han GD; Department of Orthopedics, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China.
Dai J; Department of Orthopedics, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China.
Hui HX; Department of Medical Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China.
Zhu J; Department of Medical Oncology, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China. hayyxzhuj@njmu.edu.cn.

J Orthop Surg Res ; 18(1): 446, 2023 Jun 22.

Article in En | MEDLINE | ID: mdl-37344882

Subject(s)

Bone Neoplasms; Osteosarcoma; Adolescent; Child; Humans; beta Catenin/genetics; beta Catenin/metabolism; Cell Line, Tumor; Cell Movement/genetics; Bone Neoplasms/pathology; Prognosis; Osteosarcoma/pathology; Cell Proliferation/genetics; Gene Expression Regulation, Neoplastic/genetics; Tumor Microenvironment/genetics; 5-Lipoxygenase-Activating Proteins/genetics; 5-Lipoxygenase-Activating Proteins/metabolism

Key words

ALOX5AP; Biomarker; Immune infiltration; Machine learning; Metastasis; Osteosarcoma; WNT/ßcatenin signaling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma Type of study: Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Humans Language: En Journal: J Orthop Surg Res Year: 2023 Document type: Article

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