Alpha-lipoic acid modulates the diabetes mellitus-mediated neuropathic pain via inhibition of the TRPV1 channel, apoptosis, and oxidative stress in rats.

Yazgan, Betül; Yazgan, Yener; Naziroglu, Mustafa

Yazgan, Betül; Yazgan, Yener; Naziroglu, Mustafa.

Affiliation

Yazgan B; Department of Physiology, Medical Faculty, Kastamonu University, Kastamonu, Türkiye, Turkey.
Yazgan Y; Department of Biophysics, Medical Faculty, Kastamonu University, Kastamonu, Türkiye, Turkey.
Naziroglu M; Neuroscience Research Center, Suleyman Demirel University, Isparta, Türkiye, Turkey. mustafanaziroglu@sdu.edu.tr.

J Bioenerg Biomembr ; 55(3): 179-193, 2023 06.

Article in En | MEDLINE | ID: mdl-37357235

Subject(s)

Diabetes Mellitus, Experimental; Neuralgia; Thioctic Acid; Rats; Animals; Rats, Wistar; Thioctic Acid/pharmacology; Thioctic Acid/therapeutic use; Reactive Oxygen Species/metabolism; Diabetes Mellitus, Experimental/complications; Diabetes Mellitus, Experimental/drug therapy; Oxidative Stress; Apoptosis; Neuralgia/drug therapy; Ganglia, Spinal/metabolism; TRPV Cation Channels/metabolism; TRPV Cation Channels/pharmacology

Key words

Alpha-lipoic acid; Apoptosis; Neuropathic pain; Oxidative stress; TRPV1 channel

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Thioctic Acid / Diabetes Mellitus, Experimental / Neuralgia Limits: Animals Language: En Journal: J Bioenerg Biomembr Year: 2023 Document type: Article

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