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Application of cellulose to chromatographic media: Cellulose dissolution, and media fabrication and derivatization.
Yao, Tian; Song, Jialing; Hong, Yihang; Gan, Ya; Ren, Xingfa; Du, Kaifeng.
Affiliation
  • Yao T; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal industralization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
  • Song J; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal industralization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
  • Hong Y; Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
  • Gan Y; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal industralization, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.
  • Ren X; Welch Materials, Inc. Shanghai 200237, China.
  • Du K; Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu 610065, China. Electronic address: kfdu@scu.edu.cn.
J Chromatogr A ; 1705: 464202, 2023 Aug 30.
Article in En | MEDLINE | ID: mdl-37423075
ABSTRACT
As the cornerstone of chromatographic technology, the development of high-performance chromatographic media is a crucial means to enhance the purification efficiency of biological macromolecules. Cellulose is a popular biological separation medium due to its abundant hydroxyl group on the surface, easy modification and, weak non-specific adsorption. In this paper, the development of cellulosic solvent systems, typical preparation methods of cellulosic chromatographic media, and the enhancement of chromatographic properties of cellulosic chromatographic media by polymeric ligand grafting strategies and their mechanism of action are reviewed. Ultimately, based on the current research status, a promising outlook for the preparation of high-performance cellulose-based chromatographic media was presented.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellulose / Chromatography Language: En Journal: J Chromatogr A Year: 2023 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellulose / Chromatography Language: En Journal: J Chromatogr A Year: 2023 Document type: Article