Opi1-mediated transcriptional modulation orchestrates genotoxic stress response in budding yeast.

Panessa, Giovanna Marques; Tassoni-Tsuchida, Eduardo; Pires, Marina Rodrigues; Felix, Rodrigo Rodrigues; Jekabson, Rafaella; de Souza-Pinto, Nadja Cristhina; da Cunha, Fernanda Marques; Brandman, Onn; Cussiol, José Renato Rosa

Panessa, Giovanna Marques; Tassoni-Tsuchida, Eduardo; Pires, Marina Rodrigues; Felix, Rodrigo Rodrigues; Jekabson, Rafaella; de Souza-Pinto, Nadja Cristhina; da Cunha, Fernanda Marques; Brandman, Onn; Cussiol, José Renato Rosa.

Affiliation

Panessa GM; Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP 04023-900, Brazil.
Tassoni-Tsuchida E; Department of Biology, Stanford University, Stanford, CA 94305, USA.
Pires MR; Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Felix RR; Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP 04023-900, Brazil.
Jekabson R; Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP 04023-900, Brazil.
de Souza-Pinto NC; Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP 04023-900, Brazil.
da Cunha FM; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, SP 05508-900, Brazil.
Brandman O; Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP 04023-900, Brazil.
Cussiol JRR; Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.

Genetics ; 225(1)2023 08 31.

Article in En | MEDLINE | ID: mdl-37440469

Subject(s)

Saccharomyces cerevisiae Proteins; Saccharomycetales; Basic Helix-Loop-Helix Transcription Factors/metabolism; DNA Damage; Gene Expression Regulation, Fungal; Inositol/metabolism; Inositol/pharmacology; Phospholipids/metabolism; Repressor Proteins/metabolism; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism; Saccharomycetales/metabolism; Transcription Factors/genetics

Key words

DNA damage response; Opi1; genotoxic stress; inositol pyrophosphates; methyl methanesulfonate; mitochondrial function; transcriptional regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae Proteins / Saccharomycetales Language: En Journal: Genetics Year: 2023 Document type: Article

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