Medium-dose antacids versus cimetidine in the short-term treatment of duodenal ulcer.
J Clin Gastroenterol
; 8(2): 141-5, 1986 Apr.
Article
in En
| MEDLINE
| ID: mdl-3745847
ABSTRACT
Seventy-eight patients with endoscopically proven duodenal ulcer were randomly allocated to be treated with a medium dose of liquid aluminum-magnesium antacid (75 ml in five daily doses) or cimetidine (400 mg twice daily) for 4 weeks in a prospective double-blind, double-dummy study. Healing rates at completion of trial were 66.7% in the cimetidine-treated group and 71.8% in the antacid group (p, ns). Both treatments were equally effective in relieving ulcer symptoms. Among the patient variables considered, only cigarette smoking was found to have a significant negative effect on ulcer healing. These results indicate that medium doses of antacids are as effective as cimetidine in the short-term treatment of duodenal ulcer.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cimetidine
/
Duodenal Ulcer
/
Aluminum Hydroxide
/
Magnesium
/
Magnesium Hydroxide
/
Antacids
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Clin Gastroenterol
Year:
1986
Document type:
Article