Serratia marcescens Necrotizing Fasciitis of the Ankle: A Case Report.
J Am Podiatr Med Assoc
; 113(3)2023.
Article
in En
| MEDLINE
| ID: mdl-37467259
ABSTRACT
Necrotizing fasciitis is a devastating inflammatory infection requiring emergent medical treatment and surgical intervention. Even with timely management, the mortality rate of necrotizing fasciitis approaches 25%. The causative bacteria invade fascial planes and express toxins that advance rapidly. Here, we document a rare case of necrotizing fasciitis from Serratia marcescens infection. Serratia marcescens is capable of inducing a necrotizing inflammatory cascade mediated by extracellular cytotoxin and lipase. In this case report, a 90-year-old man presented to our emergency department from a long-term care facility with a relatively benign-appearing ulcer with surrounding cellulitis on the right ankle. Blood cultures and wound cultures confirmed the organism to be S marcescens. A multidisciplinary team was consulted for management. The patient received antibiotic therapy and medical support, but because of his comorbid conditions and social situation, the designated medical decision maker opted for comfort care rather than aggressive surgical debridement. The patient progressed through the clinical stages of necrotizing fasciitis. Within 36 hours, the patient died as result of sepsis-induced organ failure.
Full text:
1
Collection:
01-internacional
Health context:
3_ND
Database:
MEDLINE
Main subject:
Serratia Infections
/
Fasciitis, Necrotizing
Type of study:
Prognostic_studies
Limits:
Aged80
/
Humans
/
Male
Language:
En
Journal:
J Am Podiatr Med Assoc
Year:
2023
Document type:
Article