ceRNA networks in gynecological cancers progression and resistance.
J Drug Target
; 31(9): 920-930, 2023 12.
Article
in En
| MEDLINE
| ID: mdl-37724808
ABSTRACT
Gynecological cancers are the second most common types of cancer in women. Clinical diagnosis of these cancers is often delayed or misdiagnosed due to lack of insight into their tumorigenesis mechanism and specific diagnostic biomarkers. Many studies have demonstrated that competing endogenous RNAs (ceRNAs) modulate the progression and resistance of gynecological cancer through microRNA (miRNA)-mediated mechanisms, which affect gene expression in multiple cancer-related pathways. Here we review studies on the involvement of the ceRNA hypothesis in the progression and resistance of gynaecological cancers to validate some ceRNAs as therapeutic targets and predictive biomarkers.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
MicroRNAs
/
RNA, Long Noncoding
/
Neoplasms
Limits:
Female
/
Humans
Language:
En
Journal:
J Drug Target
Year:
2023
Document type:
Article