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Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade.
Rowe, Jared H; Elia, Ilaria; Shahid, Osmaan; Gaudiano, Emily F; Sifnugel, Natalia E; Johnson, Sheila; Reynolds, Amy G; Fung, Megan E; Joshi, Shakchhi; LaFleur, Martin W; Park, Joon Seok; Pauken, Kristen E; Rabinowitz, Joshua D; Freeman, Gordon J; Haigis, Marcia C; Sharpe, Arlene H.
Affiliation
  • Rowe JH; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Elia I; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Shahid O; Lay Institute of Immunology and Inflammation, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
  • Gaudiano EF; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Sifnugel NE; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Johnson S; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Reynolds AG; Lay Institute of Immunology and Inflammation, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
  • Fung ME; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Joshi S; Lay Institute of Immunology and Inflammation, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
  • LaFleur MW; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Park JS; Lay Institute of Immunology and Inflammation, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
  • Pauken KE; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Rabinowitz JD; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Freeman GJ; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
  • Haigis MC; Lay Institute of Immunology and Inflammation, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.
  • Sharpe AH; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
Cancer Discov ; 13(12): 2566-2583, 2023 12 12.
Article in En | MEDLINE | ID: mdl-37728660
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: Cancer Discov Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: Cancer Discov Year: 2023 Document type: Article