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Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, Ivano; Emmenegger, Lisa; Zappulo, Alessandra; Rybak-Wolf, Agnieszka; Wurmus, Ricardo; Martinez, Anna Oliveras; Jara, Cledi Cerda; Boltengagen, Anastasiya; Hessler, Talé; Mastrobuoni, Guido; Kempa, Stefan; Zinzen, Robert; Woehler, Andrew; Rajewsky, Nikolaus.
Affiliation
  • Legnini I; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany. ivano.legnini@fht.org.
  • Emmenegger L; Human Technopole, Milan, Italy. ivano.legnini@fht.org.
  • Zappulo A; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Rybak-Wolf A; Systems Biology of Neural Tissue Differentiation, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Wurmus R; Human Technopole, Milan, Italy.
  • Martinez AO; Organoid Platform, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Jara CC; Bioinformatics and Omics Data Science, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Boltengagen A; Systems Biology Imaging Platform, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Hessler T; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Mastrobuoni G; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Kempa S; Laboratory for Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Zinzen R; Proteomic and Metabolomics Platform, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Woehler A; Proteomic and Metabolomics Platform, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
  • Rajewsky N; Systems Biology of Neural Tissue Differentiation, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
Nat Methods ; 20(10): 1544-1552, 2023 Oct.
Article in En | MEDLINE | ID: mdl-37735569
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hedgehog Proteins / Optogenetics Limits: Humans Language: En Journal: Nat Methods Year: 2023 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hedgehog Proteins / Optogenetics Limits: Humans Language: En Journal: Nat Methods Year: 2023 Document type: Article