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Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function.
Zhang, Qian; Basappa, Johnvesly; Wang, Hong Y; Nunez-Cruz, Selene; Lobello, Cosimo; Wang, Shengchun; Liu, Xiaobin; Chekol, Seble; Guo, Lili; Ziober, Amy; Nejati, Reza; Shestov, Alex; Feldman, Michael; Glickson, Jerry D; Turner, Suzanne D; Blair, Ian A; Van Dang, Chi; Wasik, Mariusz A.
Affiliation
  • Zhang Q; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Basappa J; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Wang HY; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Nunez-Cruz S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lobello C; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Wang S; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Liu X; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chekol S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Guo L; Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
  • Ziober A; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Nejati R; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Shestov A; Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
  • Feldman M; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Glickson JD; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Turner SD; Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.
  • Blair IA; Department of Pathology, University of Cambridge, Cambridge, UK.
  • Van Dang C; Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.
  • Wasik MA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Leukemia ; 37(12): 2436-2447, 2023 12.
Article in En | MEDLINE | ID: mdl-37773266

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptor Protein-Tyrosine Kinases / Lymphoma, Large-Cell, Anaplastic Limits: Humans Language: En Journal: Leukemia Year: 2023 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptor Protein-Tyrosine Kinases / Lymphoma, Large-Cell, Anaplastic Limits: Humans Language: En Journal: Leukemia Year: 2023 Document type: Article