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Opiate anticipation, opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt receptor antagonist suvorexant, while opiate analgesia is maintained.
McGregor, Ronald; Wu, Ming-Fung; Thannickal, Thomas C; Siegel, Jerome M.
Affiliation
  • McGregor R; University of California, Los Angeles.
  • Wu MF; University of California, Los Angeles.
  • Thannickal TC; University of California, Los Angeles.
  • Siegel JM; University of California, Los Angeles.
bioRxiv ; 2024 Feb 17.
Article in En | MEDLINE | ID: mdl-37790444
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Document type: Article