Melatonin attenuates inflammation and cardiac dysfunction in myocardial infarction by regulating the miRNA-200b-3p/high mobility group box chromosomal protein 1 axis.

Liu, Z H; Wu, F; Ren, K; Huo, J L

Liu, Z H; Wu, F; Ren, K; Huo, J L.

Affiliation

Liu ZH; Department of Cardiovascular Surgery, Air Force 986 Hospital, Air Force Medical University, Xi'an City, Shaanxi Province, China.
Wu F; Department of Cardiovascular Surgery, Air Force 986 Hospital, Air Force Medical University, Xi'an City, Shaanxi Province, China.
Ren K; Department of Cardiovascular Surgery, Air Force 986 Hospital, Air Force Medical University, Xi'an City, Shaanxi Province, China.
Huo JL; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an City, Shaanxi Province, China. huojunlifmmu@hotmail.com.

J Physiol Pharmacol ; 74(4)2023 Aug.

Article in En | MEDLINE | ID: mdl-37865955

Subject(s)

HMGB1 Protein; Melatonin; MicroRNAs; Myocardial Infarction; Rats; Animals; MicroRNAs/genetics; MicroRNAs/metabolism; Melatonin/pharmacology; Melatonin/therapeutic use; Melatonin/metabolism; HMGB1 Protein/genetics; HMGB1 Protein/metabolism; HMGB1 Protein/pharmacology; Signal Transduction/physiology; Myocardial Infarction/drug therapy; Myocardial Infarction/metabolism; Inflammation/drug therapy; Inflammation/metabolism; Apoptosis; Hypoxia; Myocytes, Cardiac/metabolism

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: HMGB1 Protein / MicroRNAs / Melatonin / Myocardial Infarction Limits: Animals Language: En Journal: J Physiol Pharmacol Year: 2023 Document type: Article

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