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A new histone deacetylase inhibitor remodels the tumor microenvironment by deletion of polymorphonuclear myeloid-derived suppressor cells and sensitizes prostate cancer to immunotherapy.
Chen, Zude; Yang, Xiaoshuang; Chen, Zugen; Li, Minzhao; Wang, Wei; Yang, Riwei; Wang, Zuomin; Ma, Yuxiang; Xu, Yulong; Ao, Shan; Liang, Leqi; Cai, Chao; Wang, Changning; Deng, Tuo; Gu, Di; Zhou, Hongqing; Zeng, Guohua.
Affiliation
  • Chen Z; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Yang X; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Chen Z; Department of Plastic Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi, China.
  • Li M; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Wang W; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Yang R; The Second Ward of Urology, Qujing Affiliated Hospital of Kunming Medical University, Qujing, China.
  • Wang Z; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Ma Y; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Xu Y; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Ao S; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Liang L; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Cai C; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Wang C; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Deng T; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Gu D; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Zhou H; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. sveong@163.com.
  • Zeng G; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. 1113293685@qq.com.
BMC Med ; 21(1): 402, 2023 10 25.
Article in En | MEDLINE | ID: mdl-37880708
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Myeloid-Derived Suppressor Cells Limits: Animals / Humans / Male Language: En Journal: BMC Med Year: 2023 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Myeloid-Derived Suppressor Cells Limits: Animals / Humans / Male Language: En Journal: BMC Med Year: 2023 Document type: Article