Curcumin nanoparticles and the therapeutic potential of curcumin for musculoskeletal disorders.
Eur Rev Med Pharmacol Sci
; 27(20): 9680-9702, 2023 Oct.
Article
in En
| MEDLINE
| ID: mdl-37916332
ABSTRACT
Musculoskeletal disorders (MSD) are a collection of degenerative conditions impacting the body's bones, joints, muscles, tendons, ligaments, and nerves. MSDs affect approximately 1.71 billion individuals worldwide and are a significant cause of disability. Curcumin is a polyphenolic compound with anti-inflammatory, antioxidant, and antitumor properties. In this review, we will discuss the research progress of structural analogs, derivatives, and nanomaterials that can improve the bioavailability of this natural drug. Curcumin may potentially retard the progression of osteoporosis, osteoarthritis, and rheumatoid arthritis. These effects may be related to curcumin's targeting of multiple signalling pathways.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoarthritis
/
Musculoskeletal Diseases
/
Curcumin
/
Nanoparticles
Limits:
Humans
Language:
En
Journal:
Eur Rev Med Pharmacol Sci
Year:
2023
Document type:
Article