Amelioration of 5-Fluorouracil Induced Nephrotoxicity by <i>Acacia catechu</i> through Overcoming Oxidative Damage and Inflammation in Wistar Rats.

Gadekar, Gayatri Jaising; Bhandare, Pranali Anandrao; Bandawane, Deepti Dinesh

Amelioration of 5-Fluorouracil Induced Nephrotoxicity by Acacia catechu through Overcoming Oxidative Damage and Inflammation in Wistar Rats.

Gadekar, Gayatri Jaising; Bhandare, Pranali Anandrao; Bandawane, Deepti Dinesh.

Affiliation

Gadekar GJ; Department of Pharmacology, P. E. Society's Modern College of Pharmacy, Nigdi, Pune- 44, India.
Bhandare PA; Department of Pharmacology, P. E. Society's Modern College of Pharmacy, Nigdi, Pune- 44, India.
Bandawane DD; Department of Pharmacology, P. E. Society's Modern College of Pharmacy, Nigdi, Pune- 44, India.

Cardiovasc Hematol Disord Drug Targets ; 23(3): 189-201, 2023.

Article in En | MEDLINE | ID: mdl-37946347

Subject(s)

Acacia; Antioxidants; Rats; Animals; Rats, Wistar; Antioxidants/pharmacology; Antioxidants/therapeutic use; Catalase/metabolism; Catalase/pharmacology; Acacia/metabolism; Fluorouracil/toxicity; Fluorouracil/metabolism; Creatinine/metabolism; Creatinine/pharmacology; Tumor Necrosis Factor-alpha; Uric Acid/metabolism; Uric Acid/pharmacology; Oxidative Stress; Kidney; Inflammation/drug therapy; Superoxide Dismutase/metabolism; Superoxide Dismutase/pharmacology; Urea/metabolism; Urea/pharmacology; Biomarkers

Key words

5-FU; Acacia catechu; TNF-α; antioxidant enzymes.; nephroprotective; nephrotoxicity; renal biomarkers

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acacia / Antioxidants Limits: Animals Language: En Journal: Cardiovasc Hematol Disord Drug Targets Year: 2023 Document type: Article

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