Prdx6 Regulates Nlrp3 Inflammasome Activation-Driven Inflammatory Response in Lens Epithelial Cells.

Chhunchha, Bhavana; Kumar, Rakesh; Kubo, Eri; Thakur, Priyanka; Singh, Dhirendra P

Chhunchha, Bhavana; Kumar, Rakesh; Kubo, Eri; Thakur, Priyanka; Singh, Dhirendra P.

Affiliation

Chhunchha B; Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Kumar R; Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Kubo E; Department of Ophthalmology, Kanazawa Medical University, Kahoku 9200293, Ishikawa, Japan.
Thakur P; Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Singh DP; Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Int J Mol Sci ; 24(22)2023 Nov 13.

Article in En | MEDLINE | ID: mdl-38003466

Subject(s)

Antioxidants; Inflammasomes; Reactive Oxygen Species/metabolism; Antioxidants/metabolism; Inflammasomes/metabolism; Oxidative Stress; Peroxiredoxin VI/genetics; Peroxiredoxin VI/metabolism; Epithelial Cells/metabolism; NLR Family, Pyrin Domain-Containing 3 Protein/genetics; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism

Key words

Caspase-1; GSDMD; IL-1ß; NF-Ä¸B; Nlrp3; Peroxiredoxin 6; oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammasomes / Antioxidants Language: En Journal: Int J Mol Sci Year: 2023 Document type: Article

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