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An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022.
Nabeshima, Takeshi; Ngwe Tun, Mya Myat; Thuy, Nguyen Thi Thu; Hang, Nguyen Le Khanh; Mai, Le Thi Quynh; Hasebe, Futoshi; Takamatsu, Yuki.
Affiliation
  • Nabeshima T; Department of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki, Japan.
  • Ngwe Tun MM; Kenya Research Station, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Thuy NTT; Department of Virology, Institute of Tropical Medicine, Nagasaki University (ITM-NU), Nagasaki, Japan.
  • Hang NLK; DEJIMA Infectious Disease Research Alliance, Nagasaki University, Nagasaki, Japan.
  • Mai LTQ; Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Hasebe F; Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Takamatsu Y; Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
J Med Virol ; 95(11): e29255, 2023 11.
Article in En | MEDLINE | ID: mdl-38009688
ABSTRACT
In 2022, a large dengue outbreak was reported in Vietnam, where dengue was endemic. A total of 1889 acute-phase serum samples were collected from patients with suspected dengue at Vung Tau General Hospital, the core hospital in Vung Tau Province, southern Vietnam. Among the 1889 samples analyzed for laboratory confirmation of dengue virus (DENV) infection, 339 positive cases were identified, of which 130 were primary infections and 209 were secondary infections. DENV-2 was the dominant serotype in both primary and secondary infection groups. Phylogenetic analysis based on sequences of the envelope protein-coding region revealed the emergence of a new DENV-2 lineage during this outbreak.
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Dengue / Dengue Virus Limits: Humans Country/Region as subject: Asia Language: En Journal: J Med Virol Year: 2023 Document type: Article

Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Dengue / Dengue Virus Limits: Humans Country/Region as subject: Asia Language: En Journal: J Med Virol Year: 2023 Document type: Article