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CCL2 chemokine inhibition primes the tumor vasculature for improved nanomedicine delivery and efficacy.
Möckel, Diana; Bartneck, Matthias; Niemietz, Patricia; Wagner, Maike; Ehling, Josef; Rama, Elena; Weiler, Marek; Gremse, Felix; Eulberg, Dirk; Pola, Robert; Pechar, Michal; Etrych, Tomas; Storm, Gert; Kiessling, Fabian; Tacke, Frank; Lammers, Twan.
Affiliation
  • Möckel D; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Bartneck M; Department of Medicine III, Medical Faculty, RWTH Aachen University Clinic, Aachen, Germany.
  • Niemietz P; Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Charité Campus Mitte, Charité - Universitätsmedizin Berlin, Germany.
  • Wagner M; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Ehling J; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Rama E; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Weiler M; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Gremse F; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany; Gremse-IT GmbH, Aachen, Germany.
  • Eulberg D; TME Pharma AG, Berlin, Germany.
  • Pola R; Czech Academy of Sciences, Institute of Macromolecular Chemistry, Prague, Czech Republic.
  • Pechar M; Czech Academy of Sciences, Institute of Macromolecular Chemistry, Prague, Czech Republic.
  • Etrych T; Czech Academy of Sciences, Institute of Macromolecular Chemistry, Prague, Czech Republic.
  • Storm G; Department of Pharmaceutics, Utrecht University, the Netherlands; Department of Biomaterials, Science and Technology, University of Twente, the Netherlands; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Kiessling F; Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany.
  • Tacke F; Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum and Charité Campus Mitte, Charité - Universitätsmedizin Berlin, Germany.
  • Lammers T; Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, RWTH Aachen University Clinic, Aachen, Germany. Electronic address: tlammers@ukaachen.de.
J Control Release ; 365: 358-368, 2024 Jan.
Article in En | MEDLINE | ID: mdl-38016488

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemokine CCL2 / Neoplasms Limits: Animals Language: En Journal: J Control Release Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemokine CCL2 / Neoplasms Limits: Animals Language: En Journal: J Control Release Year: 2024 Document type: Article