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XTX301, a Tumor-Activated Interleukin-12 Has the Potential to Widen the Therapeutic Index of IL12 Treatment for Solid Tumors as Evidenced by Preclinical Studies.
Patel, Ekta; Malkova, Natalia V; Crowe, David; Pederzoli-Ribeil, Magali; Fantini, Damiano; Fanny, Manoussa; Madala, Hanumantha Rao; Jenkins, Kurt A; Yerov, Oleg; Greene, Justin; Guzman, Wilson; O'Toole, Caitlin; Taylor, Jacob; O'Donnell, Rebekah K; Johnson, Parker; Lanter, Bernard B; Ames, Brian; Chen, Jia; Vu, Sallyann; Wu, Hsin-Jung; Cantin, Susan; McLaughlin, Megan; Hsiao, Yu-Shan S; Tomar, Dheeraj S; Rozenfeld, Raphael; Thiruneelakantapillai, Lakshmanan; O'Hagan, Ronan C; Nicholson, Benjamin; O'Neil, Jennifer; Bialucha, Carl Uli.
Affiliation
  • Patel E; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Malkova NV; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Crowe D; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Pederzoli-Ribeil M; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Fantini D; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Fanny M; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Madala HR; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Jenkins KA; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Yerov O; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Greene J; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Guzman W; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • O'Toole C; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Taylor J; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • O'Donnell RK; Independent Researcher, Boston, Massachusetts.
  • Johnson P; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Lanter BB; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Ames B; Werfen Therapeutics, Bedford, Massachusetts.
  • Chen J; Alnylam Pharmaceuticals, Cambridge, Massachusetts.
  • Vu S; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Wu HJ; Tango Therapeutics, Bedford, Massachusetts.
  • Cantin S; Jnana Therapeutics, Boston, Massachusetts.
  • McLaughlin M; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Hsiao YS; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Tomar DS; Kisbee Therapeutics, Cambridge, Massachusetts.
  • Rozenfeld R; Wrench Bio, Watertown, Massachusetts.
  • Thiruneelakantapillai L; Orna Therapeutics, Watertown, Massachusetts.
  • O'Hagan RC; Apricity Health, Houston, Texas.
  • Nicholson B; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • O'Neil J; Xilio Therapeutics, Inc., Waltham, Massachusetts.
  • Bialucha CU; Xilio Therapeutics, Inc., Waltham, Massachusetts.
Mol Cancer Ther ; 23(4): 421-435, 2024 Apr 02.
Article in En | MEDLINE | ID: mdl-38030380
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-12 / Neoplasms Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Year: 2024 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-12 / Neoplasms Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Year: 2024 Document type: Article