Local versus General Anaesthesia for Transcatheter Aortic Valve Implantation (TAVI): A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomised and Propensity-Score Matched Studies.
Curr Probl Cardiol
; 49(3): 102360, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-38128636
ABSTRACT
Transcatheter aortic valve implantation (TAVI) is a common practice for severe aortic stenosis, but the choice between general (GA) and local anesthesia (LA) remains uncertain. We conducted a comprehensive literature review until April 2023, comparing the safety and efficacy of LA versus GA in TAVI procedures. Our findings indicate significant advantages of LA, including lower 30-day mortality rates (RR 0.69; 95% CI [0.58, 0.82]; p < 0.001), shorter in-hospital stays (mean difference -0.91 days; 95% CI [-1.63, -0.20]; p = 0.01), reduced bleeding/transfusion incidents (RR 0.64; 95% CI [0.48, 0.85]; p < 0.01), and fewer respiratory complications (RR 0.56; 95% CI [0.42, 0.76], p<0.01). Other operative outcomes were comparable. Our findings reinforce prior evidence, presenting a compelling case for LA's safety and efficacy. While patient preferences and clinical nuances must be considered, our study propels the discourse towards a more informed anaesthesia approach for TAVI procedures.
Key words
Full text:
1
Collection:
01-internacional
Health context:
6_ODS3_enfermedades_notrasmisibles
Database:
MEDLINE
Main subject:
Aortic Valve Stenosis
/
Randomized Controlled Trials as Topic
/
Propensity Score
/
Transcatheter Aortic Valve Replacement
/
Anesthesia, General
/
Anesthesia, Local
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Curr Probl Cardiol
Year:
2024
Document type:
Article