Association of preoperative neutrophil-lymphocyte ratios with the emergence delirium in pediatric patients after tonsillectomy and adenoidectomy: an observational prospective study.
J Anesth
; 38(2): 206-214, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38267728
ABSTRACT
PURPOSE:
The study aimed to investigate potential risk factors for emergence delirium (ED) in pediatric patients after tonsillectomy and adenoidectomy (T&A).METHODS:
This prospective, single-center observational study enrolled children aged 3-7 years who underwent T&A under general anesthesia. ED was assessed according to DSM-IV or V criteria. Receiver operating characteristic curve analysis was performed to evaluate the predicative and cut-off values of risk factors, including age, preoperative anxiety level, postoperative pain and neutrophil-lymphocyte ratio (NLR) for ED. Univariate and multivariate logistic regression analyses were performed to investigate risk factors for ED.RESULTS:
94 pediatric patients who underwent T&A were enrolled and 19 developed ED (an incidence of 25.3%). Receiver operating characteristic analysis indicated that preoperative NLR was a significant predictor of ED with a cut-off value of 0.8719 and an area under the curve (AUC) of 0.671 (95% confidence interval (CI) 0.546-0.796, P = 0.022). Preoperative NLR (< 0.8719) and postoperative pain were independent risk factors associated with ED (odds ratio 0.168, 95% CI 0.033-0.858, P = 0.032; odds ratio 7.298, 95% CI 1.563-34.083, P = 0.011) according to multivariate logistic regression analysis.CONCLUSIONS:
Preoperative NLR level and postoperative pain were independent risk factors for ED in pediatric patients undergoing T&A.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tonsillectomy
/
Emergence Delirium
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Child
/
Humans
Language:
En
Journal:
J Anesth
Year:
2024
Document type:
Article