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Feasibility of abdominal fat quantification on MRI and impact on effectiveness of abdominal compression for radiotherapy motion management.
Daly, M; McDaid, L; Nelder, C; Chuter, R; Choudhury, A; McWilliam, A; Radhakrishna, G; Eccles, C L.
Affiliation
  • Daly M; Division of Clinical Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Northern Ireland, United Kingdom.
  • McDaid L; Department of Radiotherapy, The Christie NHSFT, Wilmslow Road, Manchester M20 4BX, Northern Ireland, United Kingdom.
  • Nelder C; Department of Radiotherapy, The Christie NHSFT, Wilmslow Road, Manchester M20 4BX, Northern Ireland, United Kingdom.
  • Chuter R; Division of Clinical Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Northern Ireland, United Kingdom.
  • Choudhury A; Department of Medical Physics and Engineering, The Christie NHSFT, Wilmslow Road, Manchester M20 4BX, Northern Ireland, United Kingdom.
  • McWilliam A; Division of Clinical Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Northern Ireland, United Kingdom.
  • Radhakrishna G; Department of Clinical Oncology, The Christie NHSFT, Wilmslow Road, Manchester M20 4BX, Northern Ireland, United Kingdom.
  • Eccles CL; Division of Clinical Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Northern Ireland, United Kingdom.
Article in En | MEDLINE | ID: mdl-38269244
ABSTRACT
The impact of fat on abdominal compression effectiveness in abdominal cancers was determined using magnetic resonance imaging (MRI). Visceral and subcutaneous fat were delineated on T2W 3D MRI, and motion change with compression was measured on 2D cine MRI. Results from 16 participants showed no correlation between fat percentage, body mass index (BMI), and motion change. Median BMI was 28.7 (SD, 4.9). Mean motion reduction was 7.8 mm (IQR, 5.0; p = 0.001) with compression. While no direct link was found between fat, BMI, and compression effectiveness, abdominal compression remains crucial for motion management in radiotherapy planning, providing dosimetric benefits.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Tech Innov Patient Support Radiat Oncol Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Tech Innov Patient Support Radiat Oncol Year: 2024 Document type: Article