[Two Cases of Advanced Recurrent Breast Cancer with Severe Heart Failure Caused By Anthracycline].
Gan To Kagaku Ryoho
; 50(13): 1736-1738, 2023 Dec.
Article
in Ja
| MEDLINE
| ID: mdl-38303190
ABSTRACT
Case 1 A 48-year-old woman, had right breast cancer with multiple liver metastases. Seven courses of paclitaxel plus bevacizumab were administered, but due to disease progression, 12 courses of FEC 75(total epirubicin 900 mg/m2)were administered. 2 months after the last FEC administration, the patient developed heart failure and died about 3 months later. Case 2 A 58-year-old woman, was on endocrine therapy after surgery for left breast cancer. Recurrence of lung and bone metastases were appeared 5 years after surgery, 10 courses of FEC 75(total epirubicin 750 mg/m2)were administered due to disease progression. Eight months after the last administration of FEC, the patient developed heart failure and died about 8 months later. Anthracycline induced cardiotoxicity is irreversible and has a severe course. Therefore, anthracycline should be administered with caution.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Breast Neoplasms
/
Anthracyclines
/
Heart Failure
Limits:
Female
/
Humans
/
Middle aged
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2023
Document type:
Article