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Risk assessment for mortality in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: A retrospective cohort study.
Oraii, Alireza; Shafeghat, Melika; Ashraf, Haleh; Soleimani, Abbas; Kazemian, Sina; Sadatnaseri, Azadeh; Saadat, Naser; Danandeh, Khashayar; Akrami, Ashley; Balali, Pargol; Fatahi, Mohamadreza; Karbalai Saleh, Shahrokh.
Affiliation
  • Oraii A; Students' Scientific Research Center Tehran University of Medical Sciences Tehran Iran.
  • Shafeghat M; School of Medicine Tehran University of Medical Sciences Tehran Iran.
  • Ashraf H; Feinberg School of Medicine Northwestern University Chicago Illinois USA.
  • Soleimani A; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran Iran.
  • Kazemian S; Research Development Center, Sina Hospital Tehran University of Medical Sciences Tehran Iran.
  • Sadatnaseri A; Department of Cardiology, Sina Hospital Tehran University of Medical Sciences Tehran Iran.
  • Saadat N; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran Iran.
  • Danandeh K; Department of Cardiology, Sina Hospital Tehran University of Medical Sciences Tehran Iran.
  • Akrami A; Department of Cardiology, Sina Hospital Tehran University of Medical Sciences Tehran Iran.
  • Balali P; Students' Scientific Research Center Tehran University of Medical Sciences Tehran Iran.
  • Fatahi M; Chicago College of Osteopathic Medicine Midwestern University Downers Grove Illinois USA.
  • Karbalai Saleh S; Students' Scientific Research Center Tehran University of Medical Sciences Tehran Iran.
Health Sci Rep ; 7(2): e1867, 2024 Feb.
Article in En | MEDLINE | ID: mdl-38357486
ABSTRACT
Background and

Aims:

Primary percutaneous coronary intervention (PCI) is the treatment of choice in ST-elevation myocardial infarction (STEMI) patients. This study aims to evaluate predictors of in-hospital and long-term mortality among patients with STEMI undergoing primary PCI.

Methods:

In this registry-based study, we retrospectively analyzed patients with STEMI undergoing primary PCI enrolled in the primary angioplasty registry of Sina Hospital. Independent predictors of in-hospital and long-term mortality were determined using multivariate logistic regression and Cox regression analyses, respectively.

Results:

A total of 1123 consecutive patients with STEMI were entered into the study. The mean age was 59.37 ± 12.15 years old, and women constituted 17.1% of the study population. The in-hospital mortality rate was 5.0%. Multivariate analyses revealed that older age (odds ratio [OR] 1.06, 95% confidence interval [CI] 1.02-1.10), lower ejection fraction (OR 0.97, 95% CI 0.92-0.99), lower mean arterial pressure (OR 0.95, 95% CI 0.93-0.98), and higher white blood cells (OR 1.17, 95% CI 1.06-1.29) as independent risk predictors for in-hospital mortality. Also, 875 patients were followed for a median time of 21.8 months. Multivariate Cox regression demonstrated older age (hazard ratio [HR] = 1.04, 95% CI 1.02-1.06), lower mean arterial pressure (HR = 0.98, 95% CI 0.97-1.00), and higher blood urea (HR = 1.01, 95% CI 1.00-1.02) as independent predictors of long-term mortality.

Conclusion:

We found that older age and lower mean arterial pressure were significantly associated with the increased risk of in-hospital and long-term mortality in STEMI patients undergoing primary PCI. Our results indicate a necessity for more precise care and monitoring during hospitalization for such high-risk patients.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Health Sci Rep Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Health Sci Rep Year: 2024 Document type: Article