Eight structurally diverse components with anti-acetylcholinesterase activity from Daphne bholua.
Phytochemistry
; 220: 114015, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38364884
ABSTRACT
Eight structurally diverse components, including six undescribed ones, (±)-daphuarin A (1a/1b), daphuarin B (2), daphuarin D-E (4-6), together with a pair of new natural products (±)-daphuarin C (3a/3b) were isolated from the herb of Daphne bholua Buch.-Ham. ex D. Don. Their planar structures were elucidated by extensive spectroscopic analyses. The configurations were established with the assistance of quantum chemical calculations, together with the Custom DP4+ method. The inhibitory potentials of all isolates against acetylcholinesterase were evaluated.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Daphne
Language:
En
Journal:
Phytochemistry
Year:
2024
Document type:
Article