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How Does Radiation Affect Curcumin Raw Material?
Rosiak, Natalia; Garbiec, Ewa; Bednarski, Waldemar; Skibinski, Robert; Lewandowska, Kornelia; Bazan-Wozniak, Aleksandra; Pietrzak, Robert; Cielecka-Piontek, Judyta; Zalewski, Przemyslaw.
Affiliation
  • Rosiak N; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
  • Garbiec E; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
  • Bednarski W; Institute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznan, Poland.
  • Skibinski R; Department of Medicinal Chemistry, Medical University of Lublin, Jaczewskiego 4, 20-090 Lublin, Poland.
  • Lewandowska K; Institute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznan, Poland.
  • Bazan-Wozniak A; Faculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland.
  • Pietrzak R; Faculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland.
  • Cielecka-Piontek J; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
  • Zalewski P; Department of Pharmacognosy and Biomaterials, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland.
Int J Mol Sci ; 25(5)2024 Feb 21.
Article in En | MEDLINE | ID: mdl-38473770
ABSTRACT
Turmeric, known for its curcuminoid-rich rhizome, particularly curcumin, exhibits notable antioxidant and antiviral properties. The likelihood of microbial contamination necessitates finding reliable techniques for subjecting the sample to radiation from this plant-based raw material. One alternative is to expose curcumin to radiation (e-beam), which was carried out as part of this research. Confirmation of the lack of curcumin decomposition was carried out using HPLC-DAD/MS techniques. Additionally, using the EPR technique, the generated free radicals were defined as radiation effects. Using a number of methods to assess the ability to scavenge free radicals (DPPH, ABTS, CUPRAC, and FRAP), a slight decrease in the activity of curcumin raw material was determined. The analysis of the characteristic bands in the FT-IR spectra allowed us to indicate changes in the phenolic OH groups as an effect of the presence of radicals formed.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Curcumin Language: En Journal: Int J Mol Sci Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Curcumin Language: En Journal: Int J Mol Sci Year: 2024 Document type: Article