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Sex as a risk factor regarding presbyopia in the rhesus monkey.
Croft, Mary Ann; Mcdonald, Jared P; Kiland, Julie; Mattison, Julie A; Roth, George S; Ingram, Don; Kaufman, Paul L.
Affiliation
  • Croft MA; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
  • Mcdonald JP; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
  • Kiland J; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
  • Mattison JA; Translational Gerontology Branch, National Institute on Aging, NIH, Dickerson, MD, United States of America.
  • Roth GS; GeroScience Inc. and Prolongevity Technologies LLC, Pylesville, MD, United States of America.
  • Ingram D; Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, United States of America.
  • Kaufman PL; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
PLoS One ; 19(4): e0300476, 2024.
Article in En | MEDLINE | ID: mdl-38635668
ABSTRACT

PURPOSE:

To determine the effect of sex as a risk factor regarding presbyopia.

METHODS:

Maximum accommodation was pharmacologically induced (40% cabachol corneal iontophoresis) in 97 rhesus monkeys (49 males and 48 females) ranging in age from 8 to 36 years old. Accommodation was measured by Hartinger coincidence refractometry.

RESULTS:

Accommodative amplitude measured refractometrically decreased with age, and the rate of change was not different between males and females (p = 0.827).

CONCLUSIONS:

Presbyopia is essentially sex neutral, and no one is spared. There may be modest variations between different populations for various reasons, but essentially it is monotonously predictable. At present there is no biological therapeutic.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Presbyopia / Lens, Crystalline Limits: Animals Language: En Journal: PLoS ONE (Online) / PLoS One / PLos ONE Year: 2024 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Presbyopia / Lens, Crystalline Limits: Animals Language: En Journal: PLoS ONE (Online) / PLoS One / PLos ONE Year: 2024 Document type: Article