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Gallbladder carcinosarcoma with a poor prognosis: A case report.
Dai, Yi; Meng, Min; Luo, Qi-Zhi; Liu, Yuan-Jun; Xiao, Fan; Wang, Chun-Hua.
Affiliation
  • Dai Y; Department of Hepatobiliary Surgery, Suining Central Hospital, Suining 629000, Sichuan Province, China. 158650601@qq.com.
  • Meng M; The Cancer Center, Suining Central Hospital, Suining 629000, Sichuan Province, China.
  • Luo QZ; Department of Pathology, Suining Central Hospital, Suining 629000, Sichuan Province, China.
  • Liu YJ; Department of Liver Surgery & Liver Transplantation, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
  • Xiao F; Department of Hepatobiliary Surgery, Suining Central Hospital, Suining 629000, Sichuan Province, China.
  • Wang CH; Department of Hepatobiliary Surgery, Suining Central Hospital, Suining 629000, Sichuan Province, China.
World J Clin Cases ; 12(10): 1817-1823, 2024 Apr 06.
Article in En | MEDLINE | ID: mdl-38660083
ABSTRACT

BACKGROUND:

Carcinosarcoma of the gallbladder is a rare malignant tumor with a very poor prognosis. To date, only approximately 100 patients have been reported in the English literature. The prognosis of this tumor type is poor, the preoperative diagnosis is difficult, and there is a possibility of a misdiagnosis. We present an unsuccessful case of carcinosarcoma of the gallbladder with a preoperative misdiagnosis and rapid early postoperative recurrence. Therefore, we have a deeper understanding of the poor prognosis of gallbladder carcinosarcoma (GBC) patients. CASE

SUMMARY:

The patient is a 65-year-old male. He was admitted to the hospital because of right upper abdomen distending pain and discomfort for half a month. Abdominal magnetic resonance imaging revealed a polycystic mass in the right lobe of the liver and the fossa of the gallbladder. After admission, the patient was diagnosed with a liver abscess, which was treated by abscess puncture drainage. Obviously, this treatment was unsuccessful. Hepatectomy and cholecystectomy were performed one month after the puncture. Postoperative pathologic examination revealed carcinosarcoma of the gallbladder, and the resected specimen contained two tumor components. One month after surgery, the patient's tumor recurred in situ and started to compress the duodenum, resulting in duodenal obstruction and bleeding. The treatment was not effective. The patient died of gastrointestinal hemorrhage and hypovolemic shock.

CONCLUSION:

Carcinosarcoma of the gallbladder is a rare malignant tumor that is easily misdiagnosed preoperatively and has a poor prognosis.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: World J Clin Cases Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: World J Clin Cases Year: 2024 Document type: Article