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Exploring potential correlations between HLA class II and the risk of microvascular complications in Japanese patients with type 1 diabetes.
Yamada, Eijiro; Kajita, Risa; Takahashi, Haruna; Horiguchi, Kazuhiko; Yoshino, Satoshi; Matsumoto, Shunichi; Okada, Shuichi; Yamada, Masanobu.
Affiliation
  • Yamada E; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan. Electronic address: eijiro.yamada@gunma-u.ac.jp.
  • Kajita R; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Takahashi H; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Horiguchi K; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Yoshino S; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Matsumoto S; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Okada S; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
  • Yamada M; Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
J Diabetes Complications ; 38(6): 108763, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38696976
ABSTRACT
Managing complications in Type 1 diabetes (T1D) remains challenging. HLA genes, particularly DR and DQ, are linked to T1D susceptibility. We studied 48 Japanese T1D inpatients and revealed associations between DRB1*0405-DQB1*0401 and DRB1*0901-DQB1*0303 haplotypes and complications, offering a new perspective for future research.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Diabetes Mellitus, Type 1 / Diabetic Angiopathies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: J Diabetes Complications Year: 2024 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Diabetes Mellitus, Type 1 / Diabetic Angiopathies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: J Diabetes Complications Year: 2024 Document type: Article