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Cellular therapies for bone repair: current insights.
Rodham, Paul; Khaliq, Farihah; Giannoudis, Vasileos; Giannoudis, Peter V.
Affiliation
  • Rodham P; Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK.
  • Khaliq F; Academic Department of Trauma and Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK.
  • Giannoudis V; Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK.
  • Giannoudis PV; Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK. pgiannoudi@aol.com.
J Orthop Traumatol ; 25(1): 28, 2024 May 24.
Article in En | MEDLINE | ID: mdl-38789881
ABSTRACT
Mesenchymal stem cells are core to bone homeostasis and repair. They both provide the progenitor cells from which bone cells are formed and regulate the local cytokine environment to create a pro-osteogenic environment. Dysregulation of these cells is often seen in orthopaedic pathology and can be manipulated by the physician treating the patient. This narrative review aims to describe the common applications of cell therapies to bone healing whilst also suggesting the future direction of these techniques.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mesenchymal Stem Cell Transplantation / Cell- and Tissue-Based Therapy Limits: Humans Language: En Journal: J Orthop Traumatol Year: 2024 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mesenchymal Stem Cell Transplantation / Cell- and Tissue-Based Therapy Limits: Humans Language: En Journal: J Orthop Traumatol Year: 2024 Document type: Article