Low androgen/progesterone or high oestrogen/androgen receptors ratio in serous ovarian cancer predicts longer survival.

Gogola-Mruk, Justyna; Pietrus, Milosz; Piechowicz, Maryla; Milian-Ciesielska, Katarzyna; Glód, Paulina; Wolnicka-Glubisz, Agnieszka; Szpor, Joanna; Ptak, Anna

Gogola-Mruk, Justyna; Pietrus, Milosz; Piechowicz, Maryla; Milian-Ciesielska, Katarzyna; Glód, Paulina; Wolnicka-Glubisz, Agnieszka; Szpor, Joanna; Ptak, Anna.

Affiliation

Gogola-Mruk J; Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Jagiellonian University, Krakow 30-387, Poland.
Pietrus M; Department of Gynecology and Oncology, Faculty of Medicine, Jagiellonian University Medical College, Kraków 31-501, Poland.
Piechowicz M; Department of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow 30-387, Poland.
Milian-Ciesielska K; Department of Pathomorphology, Faculty of Medicine, Jagiellonian University Medical College, Krakow 31-531, Poland.
Glód P; Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Jagiellonian University, Krakow 30-387, Poland; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Kracow 30-348, Poland.
Wolnicka-Glubisz A; Department of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow 30-387, Poland.
Szpor J; Department of Pathomorphology, Faculty of Medicine, Jagiellonian University Medical College, Krakow 31-531, Poland.
Ptak A; Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Jagiellonian University, Krakow 30-387, Poland. Electronic address: anna.ptak@uj.edu.pl.

Reprod Biol ; 24(3): 100917, 2024 Sep.

Article in En | MEDLINE | ID: mdl-38970978

Subject(s)

Ovarian Neoplasms; Receptors, Androgen; Receptors, Progesterone; Humans; Female; Ovarian Neoplasms/metabolism; Ovarian Neoplasms/mortality; Receptors, Androgen/metabolism; Receptors, Androgen/genetics; Receptors, Progesterone/metabolism; Receptors, Progesterone/genetics; Cell Line, Tumor; Estrogen Receptor alpha/metabolism; Estrogen Receptor alpha/genetics; Middle Aged; Prognosis; Cystadenocarcinoma, Serous/metabolism; Cystadenocarcinoma, Serous/pathology; Cystadenocarcinoma, Serous/mortality; Gene Expression Regulation, Neoplastic

Key words

Androgen receptor; Oestrogen receptor; Ovarian cancer cell lines; Progesterone receptor; Receptors expression ratio; Serous low- and high-grade ovarian cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Receptors, Androgen / Receptors, Progesterone Limits: Female / Humans / Middle aged Language: En Journal: Reprod Biol Year: 2024 Document type: Article

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