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Treatment of [99mTc]Tc-hydroxy-diphosphonate ([99mTc]Tc-HDP) extravasation using hyaluronidase.
Doornhof, Kevin R; de Lussanet de la Sablonière, Quido; Koolen, Stijn L W; Konijnenberg, Mark W.
Affiliation
  • Doornhof KR; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • de Lussanet de la Sablonière Q; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Koolen SLW; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
  • Konijnenberg MW; Department of Radiology and Nuclear Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Pharmacol Res Perspect ; 12(4): e1232, 2024 Aug.
Article in En | MEDLINE | ID: mdl-39054750
ABSTRACT
Extravasation of 99mTc-labeled radiopharmaceuticals is generally considered to require no specific intervention. In the presented case, the use of hyaluronidase could have minimized the adverse effects resulting from such an extravasation. Currently, no guidelines exist regarding the use of hyaluronidase after extravasation of [99mTc]Tc-HDP. Considering the low risk of administering hyaluronidase, it should be considered to limit the risk of injury after extravasation of [99mTc]Tc-HDP.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiopharmaceuticals / Extravasation of Diagnostic and Therapeutic Materials / Hyaluronoglucosaminidase Limits: Humans Language: En Journal: Pharmacol Res Perspect Year: 2024 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiopharmaceuticals / Extravasation of Diagnostic and Therapeutic Materials / Hyaluronoglucosaminidase Limits: Humans Language: En Journal: Pharmacol Res Perspect Year: 2024 Document type: Article