Group B Streptococcus and Intraamniotic Inflammation and Infection.
Clin Obstet Gynecol
; 67(3): 576-588, 2024 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-39061126
ABSTRACT
Intraamniotic inflammation and infection complicate 2% to 5% of term deliveries. Group B Streptococcus (GBS) is a common cause of intraamniotic infection associated with invasive neonatal disease and maternal morbidity. Universal vaginal-rectal screening for GBS colonization is recommended between 36 and 37 weeks. Intrapartum antibiotic prophylaxis is recommended for individuals with positive GBS screens and other risk factors. Intravenous penicillin is the preferred antimicrobial agent. Individuals with penicillin allergies may receive cefazolin for low-risk allergies and either clindamycin or vancomycin for high-risk allergies, depending on their antimicrobial susceptibilities. Clinical trials are underway to evaluate the safety and immunogenicity of maternal anti-GBS vaccine candidates.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications, Infectious
/
Streptococcal Infections
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Streptococcus agalactiae
/
Chorioamnionitis
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Antibiotic Prophylaxis
/
Anti-Bacterial Agents
Limits:
Female
/
Humans
/
Newborn
/
Pregnancy
Language:
En
Journal:
Clin Obstet Gynecol
Year:
2024
Document type:
Article