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Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model.
Dixon, Justin; Morton, Ben; Nkhata, Misheck J; Silman, Alan; Simiyu, Ibrahim G; Spencer, Stephen A; Van Pinxteren, Myrna; Bunn, Christopher; Calderwood, Claire; Chandler, Clare I R; Chikumbu, Edith; Crampin, Amelia C; Hurst, John R; Jobe, Modou; Kengne, Andre Pascal; Levitt, Naomi S; Moshabela, Mosa; Owolabi, Mayowa; Peer, Nasheeta; Phiri, Nozgechi; Singh, Sally J; Tamuhla, Tsaone; Tembo, Mandikudza; Tiffin, Nicki; Worrall, Eve; Yongolo, Nateiya M; Banda, Gift T; Bickton, Fanuel; Bilungula, Abbi-Monique Mamani; Bosire, Edna; Chawani, Marlen S; Chinoko, Beatrice; Chisala, Mphatso; Chiwanda, Jonathan; Drew, Sarah; Farrant, Lindsay; Ferrand, Rashida A; Gondwe, Mtisunge; Gregson, Celia L; Harding, Richard; Kajungu, Dan; Kasenda, Stephen; Katagira, Winceslaus; Kwaitana, Duncan; Mendenhall, Emily; Mensah, Adwoa Bemah Boamah; Mnenula, Modai; Mupaza, Lovemore; Mwakasungula, Maud; Nakanga, Wisdom.
Affiliation
  • Dixon J; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
  • Morton B; Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Nkhata MJ; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Silman A; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Simiyu IG; SHLS Nursing and Midwifery, Teesside University, Middlesborough, United Kingdom.
  • Spencer SA; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford University, Oxford, United Kingdom.
  • Van Pinxteren M; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Bunn C; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Calderwood C; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Chandler CIR; Faculty of Health Sciences, Department of Medicine and Chronic Disease Initiative for Africa, University of Cape Town, Cape Town, South Africa.
  • Chikumbu E; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
  • Crampin AC; College of Social Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.
  • Hurst JR; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
  • Jobe M; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Kengne AP; Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Levitt NS; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
  • Moshabela M; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
  • Owolabi M; Department of Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Peer N; School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
  • Phiri N; UCL Respiratory, University College London, London, United Kingdom.
  • Singh SJ; MRC Unit The Gambia at LSHTM, Banjul, The Gambia.
  • Tamuhla T; Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, Durban, South Africa.
  • Tembo M; Faculty of Health Sciences, Department of Medicine and Chronic Disease Initiative for Africa, University of Cape Town, Cape Town, South Africa.
  • Tiffin N; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
  • Worrall E; Centre for Genomic and Precision Medicine, University of Ibadan, Ibadan, Nigeria.
  • Yongolo NM; Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, Durban, South Africa.
  • Banda GT; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
  • Bickton F; Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom.
  • Bilungula AM; South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.
  • Bosire E; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
  • Chawani MS; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom.
  • Chinoko B; South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.
  • Chisala M; Department of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Chiwanda J; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Drew S; Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
  • Farrant L; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Ferrand RA; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Gondwe M; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Gregson CL; Department of Rehabilitation Sciences, The Kamuzu University of Health Sciences, Blantyre, Malawi.
  • Harding R; Department of Physical Medicine and Rehabilitation, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
  • Kajungu D; Brain and Mind Institute, Aga Khan University, Nairobi, Kenya.
  • Kasenda S; SAMRC Developmental Pathways for Health Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
  • Katagira W; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Kwaitana D; Health Economics and Policy Unit, The Kamuzu University of Health Sciences, Blantyre, Malawi.
  • Mendenhall E; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.
  • Mensah ABB; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
  • Mnenula M; Department of Non-communicable Diseases, Ministry of Health, Lilongwe, Malawi.
  • Mupaza L; Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Mwakasungula M; Faculty of Health Sciences, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
  • Nakanga W; The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
PLOS Glob Public Health ; 4(7): e0003434, 2024.
Article in En | MEDLINE | ID: mdl-39078807
ABSTRACT
Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one person, but its meaning remains a lively area of academic debate, and the utility of the concept beyond high-income settings is uncertain. This article presents the findings from an interdisciplinary research initiative that drew together 60 academic and applied partners working in 10 African countries to answer the questions how useful is the concept of multimorbidity within Africa? Can the concept be adapted to context to optimise its transformative potentials? During a three-day concept-building workshop, we investigated how the definition of multimorbidity was understood across diverse disciplinary and regional perspectives, evaluated the utility and limitations of existing concepts and definitions, and considered how to build a more context-sensitive, cross-cutting description of multimorbidity. This iterative process was guided by the principles of grounded theory and involved focus- and whole-group discussions during the workshop, thematic coding of workshop discussions, and further post-workshop development and refinement. Three thematic domains emerged from workshop discussions the current focus of multimorbidity on constituent diseases; the potential for revised concepts to centre the priorities, needs, and social context of people living with multimorbidity (PLWMM); and the need for revised concepts to respond to varied conceptual priorities amongst stakeholders. These themes fed into the development of an expanded conceptual model that centres the catastrophic impacts multimorbidity can have for PLWMM, families and support structures, service providers, and health systems.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: PLOS Glob Public Health Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: PLOS Glob Public Health Year: 2024 Document type: Article