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Burden of drug-resistant tuberculosis by the GeneXpert MTB/RIF assay and its clinico-epidemiological aspects at a tertiary care hospital in West Bengal.
Pal, Nupur; Ray, Raja; Kundu, Somenath; Hazra, Avijit; Sau, Singdha; Sur, Suhita; Saha, Shreya; Mallick, Wasim.
Affiliation
  • Pal N; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India. Electronic address: docnupur80@gmail.com.
  • Ray R; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Kundu S; Respiratory Medicine Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Hazra A; Pharmacology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Sau S; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Sur S; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Saha S; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
  • Mallick W; Microbiology Department, Institute of Postgraduate Medical Education and Research, 244 A.J.C.Bose Road, Kolkata, 700020, India.
Indian J Med Microbiol ; 51: 100703, 2024.
Article in En | MEDLINE | ID: mdl-39128730
ABSTRACT
Multidrug -resistant tuberculosis (MDRTB) is a serious threat to mankind. India has the highest number of MDRTB cases, although majority remain undiagnosed due to inadequate diagnostic infrastructure, leading to increased community transmission and mortality. This one-year observational retrospective study highlighted the effectiveness of the National Tuberculosis Elimination Program (NTEP) for prompt detection of drug-resistant TB by GeneXpert MTB/RIF assay and revealed its associated clinico-epidemiological factors. The overall detection rates of MTB and RRTB were 20.70 % and 20.86 % respectively. The pediatric population had 7.69 % rifampicin resistance, and HIV was strongly associated with the development of TB and RRTB (P < 0.01).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis, Multidrug-Resistant / Tertiary Care Centers / Mycobacterium tuberculosis Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Indian J Med Microbiol Year: 2024 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis, Multidrug-Resistant / Tertiary Care Centers / Mycobacterium tuberculosis Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Indian J Med Microbiol Year: 2024 Document type: Article