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Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States.
Sundararaman, Sesh A; Hanze Villavicencio, Karen L; Roper, Brianne; Wang, Ziyi; Davis, Amy K F; Mayhew, Jonathan A; Wang, Michelle L; Tang, Nina L; Soma, Vijaya L; Shust, Gail F; Feeney, Margaret E; Trehan, Indi; Weatherhead, Jill E; John, Chandy C; Gerber, Jeffrey S; Odom John, Audrey R.
Affiliation
  • Sundararaman SA; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Hanze Villavicencio KL; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Roper B; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Wang Z; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Davis AKF; Department of Pediatrics at UCSF, San Francisco, CA, USA.
  • Mayhew JA; Department of Pediatric and Adolescent Medicine, Western Michigan University School of Medicine, Kalamazoo, MI, USA.
  • Wang ML; Department of Pediatrics, Indiana University School of Medicine and Riley Hospital for Children, Indianapolis, IN, USA.
  • Tang NL; School of Medicine, University of Washington, Seattle, USA.
  • Soma VL; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
  • Shust GF; NYU Grossman School of Medicine, New York, NY, USA.
  • Feeney ME; NYU Grossman School of Medicine, New York, NY, USA.
  • Trehan I; Department of Pediatrics at UCSF, San Francisco, CA, USA.
  • Weatherhead JE; Department of Pediatrics, Global Health, and Epidemiology, University of Washington, Seattle, USA.
  • John CC; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
  • Gerber JS; Department of Pediatrics, Indiana University School of Medicine and Riley Hospital for Children, Indianapolis, IN, USA.
  • Odom John AR; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Article in En | MEDLINE | ID: mdl-39149792
ABSTRACT
Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however severe hemolysis requiring hospitalization or transfusion was rare. In children in the U.S. treated with artesunate, counseling and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pediatric Infect Dis Soc Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Pediatric Infect Dis Soc Year: 2024 Document type: Article