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Investigation of the effect of ABO blood types on the prognosis of endometrioid-type endometrial cancer.
Keser-Sahin, Havva H; Avci, Fazil; Kulhan, Mehmet; Hamid-Güler, Abdul; Can-Ates, Mete; Çelik, Çetin; Bilgi, Ahmet.
Affiliation
  • Keser-Sahin HH; Department of Pathology, Hitit University Faculty of Medicine, Çorum, Turkey.
  • Avci F; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
  • Kulhan M; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
  • Hamid-Güler A; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
  • Can-Ates M; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
  • Çelik Ç; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
  • Bilgi A; Department of Obstetric and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
Cir Cir ; 2024 Sep 23.
Article in En | MEDLINE | ID: mdl-39312280
ABSTRACT

Objective:

The aim of this study was to examine how the ABO blood type affects endometrioid-type, EC prognosis.

Method:

A total of 522 patients diagnosed with EC between February 2010 and December 2021 were assessed, retrospectively. ABO blood types were used to divide the patients into four groups as A, B, O, and AB. Demographic data, menopause, prognostic variables, FIGO stage, and survival were evaluated. A in 217 patients, B in 84 patients, O in 181 patients, and AB blood type in 40 patients were analyzed.

Results:

Age, gravida, parity, body mass index, menopause, comorbidity, prognostic variables, FIGO stage, and survival according to the groups were similar (p > 0.012). Group A differed from other groups statistically in peritoneal fluid cytology (p = 0.004). B blood type had the best chance of cumulative overall survival, followed by AB, A, and O blood types, in that order (p = 0.170).

Conclusion:

In light of blood types sensitivity to endometrioid-type EC, O blood type has been identified as blood type with the highest risk of endometrioid EC.
RESUMEN

Objetivo:

Examinar cómo los tipos de sangre ABO afectan el pronóstico del cáncer de endometrio de tipo endometrioide.

Método:

Se evaluaron retrospectivamente 522 pacientes diagnosticadas con CE entre 2010 y 2021. Se utilizaron los tipos de sangre ABO para dividir a las pacientes cuatro grupos A, B, O, y AB. Se evaluaron la edad, la menopausia, las variables pronósticas, la etapa FIGO y la supervivencia. Se determinó el tipo de sangre A en 217 pacientes, el B en 84 pacientes, el O en 181 pacientes y el AB en 40 pacientes.

Resultados:

La edad, la menopausia, las variables pronósticas, la etapa FIGO y la supervivencia según grupos fueron similares (p > 0.012). El grupo A difirió estadísticamente de los otros grupos en la citología del líquido peritoneal (p = 0.004). El tipo de sangre B tuvo mejor probabilidad de una supervivencia global acumulativa, seguido por los tipos AB, A, y 0, en este orden (p = 0.170).

Conclusión:

A la luz de la sensibilidad de los tipos de sangre al cáncer de endometrio tipo endometrioide, el O ha sido identificado como el de mayor riesgo de cáncer endometrial tipo endometrioide.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cir Cir Year: 2024 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cir Cir Year: 2024 Document type: Article